Further development of a variety of catalytic asymmetric reactions promoted by heterobimetallic asymmetric complexes such as a tandem inter- intramolecular catalytic asymmetric nitroaldol reaction, a direct catalytic asymmetric reaction of aldehydes and unmodified ketones, an enantioselective ring opening of epoxides with thiols, and a catalytic asymmetric epoxidation of a, P-unsaturated ketones are described.