PNEUMONIA: AN ELEVEN-YEAR STUDY IN A PEDIATRIC PRACTICE1

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Abstract
Murphy, T. F., F. W. Henderson (U. of North Carolina, School of Medicine, Chapel Hill, NC 27514), W. A. Clyde, Jr., A.M. Collier, and F. W. Denny. Pneumonia: an eleven-year study in a pediatric practice. Am J Epidemiol 1981;113:12-21 Data from an 11-year study of acute lower respiratory tract illness were analyzed to provide added insight into the causes and patterns of occurrence of pneumonia in an outpatient pediatric population. Over 80% of all episodes of pneumonia occurred in children less than seven years of age; the peak attack rate was observed in 2–4-year-old children. A virus or Mycoplasma pneumoniae was isolated from 24% of children with pneumonia; 57% of all episodes occurred during outbreaks for which a viral or mycoplasmal cause could usually be identified. Respiratory syncytial virus (RSV), parainfluenza viruses types 1 and 3, adenoviruses, influenza A viruses and M. pneumonlae accounted for 86% of all isolates. Attack rates of pneumonia in preschool children were highest during periods of RSV and Influenza A virus prevalence; M. pneumonlae was the most frequent isolate from school aged children. The data contained in this report augment the understanding of the causes of pneumonia in children and provide a data base for scientists interested in the prevention of lower respiratory tract illness in children.