Antibiotics from Basidiomycetes. XXXI. Aleurodiscal: An antifungal sesterterpenoid from Aleurodiscus mirabilis (Berk. & Curt.) Hoehn.

Abstract
Aleurodiscal, an antifungal antibiotic has been isolated from mycelial cultures of Aleurodiscus mirabilis (Berk. and Curt.) Hohn. It causes abnormal apical branchings of Mucor miehei hyphae at very low concentrations. The structure and absolute configuration of the antibiotic has been determined by a single crystal X-ray analysis and hydrolysis to D-(+)-xylose. Aleurodiscal is a hydroxysesterterpene aldehye .beta.-D-xyloside with a novel carbon skeleton.