Long-Term Use of the Low Dose LHRH Analogue Combined With Monthly Medroxy-Progesterone Administration

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Abstract
In a pilot study, chronic pelvic pain associated with endometriosis, dysmenorrhoea or menorrhagia has been treated for prolonged periods with low dose buserelin (daily) and medroxy-progesterone (monthly). The partial inhibition of ovarian function was effective in relieving pain and controlling uterine bleeding, with few side effects. There was no change in serum cholesterol level. A possible small bone demineralisation effect has been observed.
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