Dynamic Regulation, Desensitization, and Cross-talk in Discrete Subcellular Microdomains during β2-Adrenoceptor and Prostanoid Receptor cAMP Signaling

This publication has 41 references indexed in Scilit:

• Mapping binding sites for the PDE4D5 cAMP-specific phosphodiesterase to the N- and C-domains of β-arrestin using spot-immobilized peptide arrays
  Biochemical Journal, 2007
• PGE1 stimulation of HEK293 cells generates multiple contiguous domains with different [cAMP]: role of compartmentalized phosphodiesterases
  The Journal of cell biology, 2006
• Scanning peptide array analyses identify overlapping binding sites for the signalling scaffold proteins, β-arrestin and RACK1, in cAMP-specific phosphodiesterase PDE4D5
  Biochemical Journal, 2006
• G-protein-coupled Receptor Kinase Specificity for β-Arrestin Recruitment to the β2-Adrenergic Receptor Revealed by Fluorescence Resonance Energy Transfer
  Journal of Biological Chemistry, 2006
• An anchored PKA and PDE4 complex regulates subplasmalemmal cAMP dynamics
  The EMBO Journal, 2006
• In resting COS1 cells a dominant negative approach shows that specific, anchored PDE4 cAMP phosphodiesterase isoforms gate the activation, by basal cyclic AMP production, of AKAP-tethered protein kinase A type II located in the centrosomal region
  Cellular Signalling, 2005
• Negative Feedback Exerted by cAMP-dependent Protein Kinase and cAMP Phosphodiesterase on Subsarcolemmal cAMP Signals in Intact Cardiac Myocytes
  Journal of Biological Chemistry, 2004
• Compartmentation of G Protein-Coupled Signaling Pathways in Cardiac Myocytes
  Annual Review of Pharmacology and Toxicology, 2001
• Selective Regulation of Endogenous G Protein-coupled Receptors by Arrestins in HEK293 Cells
  Published by Elsevier ,2000
• Differential Regulation of Type I and Type VIII Ca2+-stimulated Adenylyl Cyclases by Gi-coupled Receptors in Vivo
  Published by Elsevier ,1996