Remarkable Kinetic Resolution of Chiral β-Keto Esters by Baker’s Yeast Reduction
- 1 August 1995
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1995 (08) , 837-838
- https://doi.org/10.1055/s-1995-5083
Abstract
The reduction of chiral β-keto esters with baker’s yeast is described. Reduction of 10 yields highly functionalized diol 11 with excellent stereoselectivity and generates a useful intermediate for natural product syntheses.Keywords
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