Intrahypothalamic Perfusion with lnterleukin-1-Beta Stimulates the Local Release of Corticotropin-Releasing Hormone and Arginine Vasopressin and the Plasma Adrenocorticotropin in Freely Moving Rats: A Comparative Perfusion of the Paraventricular Nucleus and the Median Eminence

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Abstract
It is almost generally accepted that an acute-phase ACTH response induced by interleukin (IL)-1 is mediated principally by CRH release from the hypothalamus. However, the precise cellular site of acti