Properdin Factor B Frequencies in Four Asian Populations

Abstract
The distribution of Properdin factor B (Bf) phenotypes and their gene frequencies were investigated in four Asian poulations (Chinese, Filipino, Thai and Japanese). The frequency of the BfS phenotype in Filipinos (0.717) was significantly lower than that in Chinese (0.900) and Thai (0.889) (p < 0.01), but not different from the Japanese (0.840). One variant, BfF₀.65S, was identified in a Japanese subject. Thus, in the Asian populations studied, Bf frequencies were high and the frequency of variants other than F and S were low.