Some prognostic factors for the development of transplant-related coronary artery disease in human cardiac allografts.

  • 1 January 1991
    • journal article
    • research article
    • Vol. 10, 38-44
Abstract
The study of endomyocardial biopsy specimens taken in the first 130 days after transplantation has yielded no histologic features predictive of later development of transplant-related coronary artery disease. This study, however, indicated that a combination of the following factors might be predictive in cyclosporine-treated patients: untreated histologically proven episodes of rejection, infection with cytomegalovirus or reactivation of infection, ischemic heart disease in the recipient as the reason for heart transplantation, and possibly HLA-B5 or -B8 mismatch.

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