Sequence of the OXA2 β‐lactamase: comparison with other penicillin‐reactive enzymes
- 21 October 1985
- journal article
- research article
- Published by Wiley in FEBS Letters
- Vol. 191 (1) , 39-44
- https://doi.org/10.1016/0014-5793(85)80989-3
Abstract
The nucleotide sequence of the unusual plasmid‐mediated OXA2 β‐lactamase is presented, and compared with other β‐lactamases. The OXA2 enzyme has similar features at the presumed active site, but no other significant regions ofhomology with other penicillin‐reactive enzymes. The active site homology may therefore represent convergent evolution of otherwise dissimilar genes.Keywords
This publication has 26 references indexed in Scilit:
- The nucleotide sequences of the ponA and ponB genes encoding penicillin‐binding proteins 1A and 1B of Escherichia coli K12European Journal of Biochemistry, 1985
- On the process of cellular division in Escherichia coli: Nucleotide sequence of the gene for penicillin-binding protein 3Molecular Genetics and Genomics, 1983
- A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragmentsGene, 1982
- A physical and genetic map of the IncN plasmid R46Plasmid, 1981
- Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencingJournal of Molecular Biology, 1980
- The structure of β-lactamasesPhilosophical Transactions of the Royal Society of London. B, Biological Sciences, 1980
- Segregation of the mutator property of plasmid R46 from its ultraviolet-protecting propertyMolecular Genetics and Genomics, 1979
- The dimeric nature of an R-factor mediated β-lactamaseBiochemical and Biophysical Research Communications, 1976
- A complementation analysis of the restriction and modification of DNA in Escherichia coliJournal of Molecular Biology, 1969
- RESISTANCE TO PENICILLINS AND ITS TRANSFER IN ENTEROBACTERIACEÆThe Lancet, 1965