Role of Endogenous and Induced Regulatory T Cells During Infections
- 23 September 2008
- journal article
- review article
- Published by Springer Nature in Journal of Clinical Immunology
- Vol. 28 (6) , 707-715
- https://doi.org/10.1007/s10875-008-9248-6
Abstract
Background Various populations of regulatory cells, including Foxp3+ TReg, have been shown to play a central role in the maintenance of peripheral homeostasis and establishment of controlled immune responses. Objective In this review, we discuss current hypotheses and points of polemic associated with the origin, mode of action, and antigen specificity of both endogenous and induced regulatory T cells during infections.Keywords
This publication has 96 references indexed in Scilit:
- Foxp3+natural regulatory T cells preferentially form aggregates on dendritic cellsin vitroand actively inhibit their maturationProceedings of the National Academy of Sciences, 2008
- Dendritic cells in intestinal immune regulationNature Reviews Immunology, 2008
- Antagonistic nature of T helper 1/2 developmental programs in opposing peripheral induction of Foxp3 + regulatory T cellsProceedings of the National Academy of Sciences, 2007
- Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17–producing T cell responsesNature Immunology, 2007
- Expansion and function of Foxp3-expressing T regulatory cells during tuberculosisThe Journal of Experimental Medicine, 2007
- CD4+CD25−Foxp3− Th1 cells are the source of IL-10–mediated immune suppression in chronic cutaneous leishmaniasisThe Journal of Experimental Medicine, 2007
- Dynamic imaging of dendritic cell extension into the small bowel lumen in response to epithelial cell TLR engagementThe Journal of Experimental Medicine, 2006
- The gut flora as a forgotten organEMBO Reports, 2006
- Toll-like receptor 2 signaling modulates the functions of CD4+CD25+regulatory T cellsProceedings of the National Academy of Sciences, 2006
- Anatomical basis of tolerance and immunity to intestinal antigensNature Reviews Immunology, 2003