Transient Hypothyroidism after Iodine-131 Treatment of Thyrotoxicosis
- 1 February 1980
- journal article
- research article
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 50 (2) , 226-229
- https://doi.org/10.1210/jcem-50-2-226
Abstract
Thirty consecutive patients with thyrotoxicosis were followed up at monthly intervals for 6 months after treatment with iodine-131. Serum total T4, serum total T3, and serum TSH response to TRH were measured at each review. Biochemical evidence of hypothyroidism (low T4 with raised basal TSH) developed in 18 patients 1–4 months after treatment. In 5 of these patients, symptoms and signs of hypothyroidism remained absent or minimal and spontaneous recovery of thyroid function occurred during the ensuing 2 months. If biochemical hypothyroidism occurs during the first 6 months- after radioiodine therapy, it is recommended that T4 replacement be withheld for 2 months unless the severity of symptoms demands treatment.Keywords
This publication has 1 reference indexed in Scilit:
- Transient Postpartum Hypothyroidism: Fourteen Cases with Autoimmune ThyroiditisAnnals of Internal Medicine, 1977