Ligand Binding to Transmembrane Receptors on Intact Cells or Membrane Vesicles Measured in a Homogeneous 1-Microliter Assay Format
Open Access
- 1 June 2001
- journal article
- Published by Elsevier in SLAS Discovery
- Vol. 6 (3) , 159-170
- https://doi.org/10.1177/108705710100600306
Abstract
No abstract availableKeywords
This publication has 26 references indexed in Scilit:
- Single-Molecule Detection Technologies in Miniaturized High Throughput Screening: Binding Assays for G Protein–Coupled Receptors Using Fluorescence Intensity Distribution Analysis and Fluorescence AnisotropySLAS Discovery, 2001
- Receptor–Ligand Interactions Studied with Homogeneous Fluorescence-Based Assays Suitable for Miniaturized ScreeningSLAS Discovery, 2001
- Single Molecule Detection Technologies in Miniaturized High Throughput Screening: Fluorescence Correlation SpectroscopySLAS Discovery, 1999
- Miniaturization of a Mammalian Cell-Based Assay: Luciferase Reporter Gene Readout in a 3 Microliter 1536-Well PlateSLAS Discovery, 1999
- A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening AssaysSLAS Discovery, 1999
- Molecular tinkering of G protein-coupled receptors: an evolutionary successThe EMBO Journal, 1999
- Differences between natural and recombinant G protein-coupled receptor systems with varying receptor/G protein stoichiometryTrends in Pharmacological Sciences, 1997
- Orphan G protein-coupled receptors: a neglected opportunity for pioneer drug discoveryPublished by Elsevier ,1997
- Reverse intrinsic activity of antagonists on G protein-coupled receptorsTrends in Pharmacological Sciences, 1992
- Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reactionBiochemical Pharmacology, 1973