Null Mutation of HvrA Compensates for Loss of an Essential relA/spoT -Like Gene in Rhodobacter capsulatus
- 1 January 2004
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 186 (1) , 235-239
- https://doi.org/10.1128/jb.186.1.235-239.2004
Abstract
We report that a single relA/spoT-like gene exists on the Rhodobacter capsulatus chromosome, and its mutational loss is lethal. This gene could be mutated only under a mutational background of a null mutation in the nucleoid protein HvrA. This result suggests that there may be a direct link between HvrA-regulated promoters and the ppGpp-related stringent response.Keywords
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