STUDIES ON THE ACTION-PATTERN OF ANTITUBERCULAR SUBSTANCES
- 1 November 1954
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Biochemistry
- Vol. 41 (6) , 695-708
- https://doi.org/10.1093/oxfordjournals.jbchem.a126488
Abstract
Oleic acid obtained from R. suganii inhibits neither conidia germination nor growth of Mycobacterium tuberculosis on a plate medium. The addition of M/50,000 oleic acid results in an excess O2-uptake by Aspergillus oryzae conidia, but it does not affect glucose utilization or CO2-evolution. Antifungal action of oleic acid occurs only in liquid media, and disappears on adding agar. The anti-fungal action of oleic acid is due to the surface activity of oleic acid, producing an anaerobic condition.This publication has 0 references indexed in Scilit: