On the Way to Liposidomycins, New Nucleoside Antibiotics. Access to the Homochiral Diazepanone Core
- 1 February 1997
- journal article
- research article
- Published by Taylor & Francis in Journal of Carbohydrate Chemistry
- Vol. 16 (2) , 129-141
- https://doi.org/10.1080/07328309708006515
Abstract
Access to the homochiral diazepanone core of liposidomycins has been carried out through the regiospecific nucleophilic opening of an enantiomerically pure α-amino-β,γ-epoxy-acid precursor, by an L-amino acid derivative, on one hand and cyclisation by a peptidic coupling reaction, on the other hand.Keywords
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