Abstract
A rapid method for detn. of salicylate in biological fluids is based on a reagent containing ferric nitrate, mercuric chloride and hydrochloric acid, which precipitates the proteins and simultaneously reacts with salicylic acid to give a purple color. The recovery of sodium salicylate added to biological fluids is quantitative. The blank values on normal serum and plasma samples are less than 1.1 mg. of salicylic acid/100 ml. The effect of some possible interfering substances is considered. A single determination occupies 5 min.

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