An update on digoxin.
Open Access
- 1 July 1989
- journal article
- research article
- Published by Oxford University Press (OUP) in Clinical Chemistry
- Vol. 35 (7) , 1326-1331
- https://doi.org/10.1093/clinchem/35.7.1326
Abstract
This review deals briefly with recent developments in the therapeutic drug monitoring of digoxin. Strategies for decreasing the interference by digoxin metabolites, digoxin-like factors, and spironolactone metabolites in immunoassays of digoxin are discussed. Other issues addressed include the development of alternative methods of analysis, such as receptor assays and "high-pressure" liquid chromatography; digoxin-like factors in hypertension; drug-drug interactions; redistribution of digoxin stores in the body; and forensic considerations.Keywords
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