Effect of aldosterone and methylprednisolone on cardiac NaK-ATPase
- 1 October 1977
- journal article
- research article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 33 (10) , 1280-1281
- https://doi.org/10.1007/bf01920133
Abstract
Aldosterone (15 μg BID) and methylprednisolone (8 mg QD) administration to female guinea-pigs augmented both the total and the specific activity of NaK-ATPase but not the activity of adenylate cyclase in the cardiac sarcolemma. The rise in NaK-ATPase was due to increase in the number of enzyme molecules; catalytic activity and ouabain-sensitivity of individual molecules did not change.Keywords
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