Absorption of moisture by sodium cromoglycate and mixtures of sodium cromoglycate and lactose
- 1 August 1983
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 35 (8) , 477-481
- https://doi.org/10.1111/j.2042-7158.1983.tb04813.x
Abstract
The presence of up to about 15% w/w moisture has little effect on the tensile and shear properties of sodium cromoglycate and of 1:1 mixtures of sodium cromoglycate and lactose. Analysis of their adsorption and desorption isotherms using equations developed by Young and Nelson shows that this is because most of the moisture is absorbed into the interior of the sodium cromoglycate leaving little adsorbed moisture on the surfaces of the particles concerned.This publication has 14 references indexed in Scilit:
- X-ray analysis of disodium cromoglycateJournal of Pharmacy and Pharmacology, 1974
- Conformation of Sodium Cromolyn in Aqueous Solution Using Light Scattering and Magnetic BirefringenceJournal of Pharmaceutical Sciences, 1973
- Mesomorphism in the System Disodium Chromoglycate-WaterMolecular Crystals and Liquid Crystals, 1973
- The failure properties of lactose and calcium carbonate powdersPowder Technology, 1972
- Effect of Moisture on Tensile Strength of Bulk Solids I: Sodium Chloride and Effect of Particle SizeJournal of Pharmaceutical Sciences, 1972
- Cohesion and tensile strength of bulk solidsRheologica Acta, 1971
- Effect of particle size upon the strength of powdersPowder Technology, 1968
- An annular shear cell for granular materialsPowder Technology, 1968
- The effect of humidity and temperature on the cohesion of powdersJournal of Pharmacy and Pharmacology, 1966
- An improved apparatus for measuring the tensile strength of powdersJournal of Scientific Instruments, 1964