Absence of the kdr mutation in the molecular ‘M’ form suggests different pyrethroid resistance mechanisms in the malaria vector mosquito Anopheles gambiae s.s.
Open Access
- 1 May 2003
- journal article
- research article
- Published by Wiley in Tropical Medicine & International Health
- Vol. 8 (5) , 420-422
- https://doi.org/10.1046/j.1365-3156.2003.01034.x
Abstract
Field tests conducted on adult Anopheles mosquitoes using standard WHO procedures, diagnostic kits and test papers in south-western Nigeria showed pyrethroid (deltamethrin and permethrin) resistance in adult populations of Anopheles gambiae sensu stricto. The knock-down resistance (kdr) mutation involved in pyrethroid resistance was only found in the molecular S form of An. gambiae s.s. even in area where both molecular M and S forms occurred in sympatry. The absence of the kdr mutation in the M form suggests an additional pyrethroid resistance mechanism in An. gambiae s.s.Keywords
This publication has 10 references indexed in Scilit:
- Resistance of the malaria vector Anopheles gambiae s.s. to pyrethroid insecticides, in south-western NigeriaPathogens and Global Health, 2002
- Evidence for genetic differentiation between the molecular forms M and S within the Forest chromosomal form of Anopheles gambiae in an area of sympatryInsect Molecular Biology, 2002
- Molecular evidence of incipient speciation within Anopheles gambiae s.s. in West AfricaInsect Molecular Biology, 2001
- Distribution of African Malaria Mosquitoes Belonging to the Anopheles gambiae ComplexParasitology Today, 2000
- Molecular characterization of pyrethroid knockdown resistance (kdr) in the major malaria vector Anopheles gambiae s.s.Insect Molecular Biology, 1998
- Polymorphisms detected by random PCR distinguish between different chromosomal forms of Anopheles gambiae.Proceedings of the National Academy of Sciences, 1994
- Ecological genetic studies in the chromosomal form Mopti ofAnopheles gambiae s.str. in Mali, West AfricaGenetica, 1994
- Reduced susceptibility of Anopheles gambiae to permethrin associated with the use of permethrin‐impregnated bednets and curtains in KenyaMedical and Veterinary Entomology, 1994
- Identification of Single Specimens of the Anopheles Gambiae Complex by the Polymerase Chain ReactionThe American Journal of Tropical Medicine and Hygiene, 1993
- Chromosomal differentiation and adaptation to human environments in the Anopheles gambiae complexTransactions of the Royal Society of Tropical Medicine and Hygiene, 1979