The Comparison of Complement Fixing and Hemolytic Activities in Several Systems

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Abstract
The determination of complement-fixing activity of the hemolytic systems compared was made possible by the use of formalin-treated erythrocytes. Such treated cells are not subject to agglutination nor to lysis. No correlation was found between the hemolysin and complement-fixing titers in these systems. This lack of correlation was explained on the basis of antibody heterogenity, i.e. antibody molecules differing in their ability to participate in a particular serological reaction.

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