α-hydroxy- and α-ketoester functionalized thrombin inhibitors
- 31 December 1992
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 2 (12) , 1607-1612
- https://doi.org/10.1016/s0960-894x(00)80440-0
Abstract
No abstract availableKeywords
This publication has 17 references indexed in Scilit:
- In Vivo Anticoagulant and Antiplatelet Effect of D-Phe-Pro-Arg-H and D-MePhe-Pro-Arg-HThrombosis and Haemostasis, 1992
- In Vitro Inhibition of Blood Coagulation by Tripeptide Aldehydes - A Retrospective Screening Study Focused on the Stable D-MePhe-Pro-Arg-H · H2SO4Thrombosis and Haemostasis, 1992
- An approach toward the total synthesis of cyclotheonamides; preparation of a C(1) to N(14) segmentTetrahedron Letters, 1992
- Reassignment of stereochemistry and total synthesis of the thrombin inhibitor cyclotheonamide BJournal of the American Chemical Society, 1992
- Thrombin structure and functionBlood Coagulation & Fibrinolysis, 1991
- Highly active and selective anticoagulants: D-Phe-Pro-Arg-H, a free tripeptide aldehyde prone to spontaneous inactivation, and its stable N-methyl derivative, D-MePhe-Pro-Arg-HJournal of Medicinal Chemistry, 1990
- .alpha.-Diketone and .alpha.-keto ester derivatives of N-protected amino acids and peptides as novel inhibitors of cysteine and serine proteinasesJournal of Medicinal Chemistry, 1990
- Synthesis of peptidyl fluoromethyl ketones and peptidyl .alpha.-keto esters as inhibitors of porcine pancreatic elastase, human neutrophil elastase, and rat and human neutrophil cathepsin GJournal of Medicinal Chemistry, 1990
- ThrombinaAnnals of the New York Academy of Sciences, 1986
- Thrombin inhibitors. 3. Carboxyl-containing amide derivatives of N.alpha.-substituted L-arginineJournal of Medicinal Chemistry, 1980