I. V. SEDATION FOR CONSERVATIVE DENTISTRY
Open Access
- 1 April 1986
- journal article
- research article
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 58 (4) , 371-377
- https://doi.org/10.1093/bja/58.4.371
Abstract
Midazolam and the emulsion formulation of diazepam were compared in a cross-over study in 50 patients undergoing out-patient conservative dentistry, with particular regard to sedation and the quality of recovery. Both agents proved effective, but sedation was achieved more rapidly with midazolam (P = 0.001) and was more effective (P < 0.02). Significantly greater antero-grade amnesia for the dental procedure (P < 0.001) and a more rapid return to normal activities (P < 0.02) were found with midazolam. Psychometric testing, however, failed to show any objective differences between the treatments. A mean dose of midazolam 0.14 mg kg−1 was required to achieve sedation equating to 0.29 mg kg−1 of diazepam, although there was considerable variation between individual patients.This publication has 0 references indexed in Scilit: