Postpartum Mania

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Abstract
Twenty-one patients with bipolar affective disorder (20 manic episodes, 1 depressive episode) during the postpartum period were evaluated. They were compared to an unselected group of women with bipolar histories and to a matched control group. The postpartum group had significantly more Schneiderian symptoms and fewer recurrences of illness within the 3-yr period after the index admission. There was a notable trend toward postpartum patients having fewer affectively ill relatives than the controls. The practical significance of these findings with regards to Li therapy is discussed, as is the theoretical significance in terms of heterogeneity of the bipolar syndrome.

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