Association of melanoma and natalizumab therapy in the Italian MS population: a second case report
- 5 November 2010
- journal article
- research article
- Published by Springer Nature in Neurological Sciences
- Vol. 32 (1) , 181-182
- https://doi.org/10.1007/s10072-010-0427-x
Abstract
There is debate about a possible association between natalizumab treatment and higher risk of melanoma. Here we report a case of melanoma in a patient who developed melanoma after 77 infusions of natalizumab, without known risk factors. Pharmacovigilance programs of new drugs can help to monitor adverse events in patients at risk.Keywords
This publication has 12 references indexed in Scilit:
- Melanoma in multiple sclerosis treated with natalizumab: causal association or coincidence?Multiple Sclerosis Journal, 2009
- Melanoma complicating treatment with Natalizumab (Tysabri) for multiple sclerosisZeitschrift für Neurologie, 2009
- Melanoma following treatment with alemtuzumab for multiple sclerosisEuropean Journal of Neurology, 2009
- More on Melanoma with TransdifferentiationNew England Journal of Medicine, 2008
- Melanoma Complicating Treatment with Natalizumab for Multiple SclerosisNew England Journal of Medicine, 2008
- Eruptive latent metastatic melanomas after initiation of antitumor necrosis factor therapiesJournal of the American Academy of Dermatology, 2007
- Melanoma incidence in central Italy will go on increasing also in the near future: A registry-based, age–period–cohort analysisEuropean Journal Of Cancer Prevention, 2007
- A Randomized, Placebo-Controlled Trial of Natalizumab for Relapsing Multiple SclerosisNew England Journal of Medicine, 2006
- Integrin signaling in malignant melanomaCancer and Metastasis Reviews, 2005
- Expression of the integrin $alpha;4$beta;1 on melanoma cells can inhibit the invasive stage of metastasis formationCell, 1994