Cadherins in embryonic and neural morphogenesis
Top Cited Papers
- 1 November 2000
- journal article
- review article
- Published by Springer Nature in Nature Reviews Molecular Cell Biology
- Vol. 1 (2) , 91-100
- https://doi.org/10.1038/35040042
Abstract
Cadherins not only maintain the structural integrity of cells and tissues but also control a wide array of cellular behaviours. They are instrumental for cell and tissue polarization, and they regulate cell movements such as cell sorting, cell migration and cell rearrangements. Cadherins may also contribute to neurite outgrowth and pathfinding, and to synaptic specificity and modulation in the central nervous system.Keywords
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