New bacteriochlorin derivatives with a fused N-aminoimide ring
- 1 November 2003
- journal article
- Published by World Scientific Pub Co Pte Ltd in Journal of Porphyrins and Phthalocyanines
- Vol. 7 (11) , 725-730
- https://doi.org/10.1142/s1088424603000902
Abstract
Upon interaction of hydrazine hydrate with bacteriopurpurin, the initially formed monohydrazide in an acidic medium readily reacts with the second carboxyl group to give a six-membered N-aminocycloimide of bacteriochlorin p6. The free amino group at the fused imide ring makes it easy to obtain N-alkyl and N-acyl derivatives. The compounds thus obtained exhibit high light-induced cytotoxicity on A549 human adenocarcinoma cells.Keywords
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