Kidney fatty acid‐binding protein: Identification as α2U‐globulin
- 27 March 1989
- journal article
- research article
- Published by Wiley in FEBS Letters
- Vol. 246 (1-2) , 101-104
- https://doi.org/10.1016/0014-5793(89)80261-3
Abstract
A fatty acid-binding protein was purified from male rat kidney by the method of Fujii et al. [(1987) Arch. Biochem. Biophys. 254, 552–558]. Based on the close similarity of amino acid composition and the identity of the amino acid sequence in the amino-terminal region, the fatty acid-binding protein was identified as α2U-globulin, which is the major male-specific protein in rat urine. The amino-terminal residue of the isolated kidney protein corresponds to residue 10 of α2U-globulin, suggesting that the protein has been proteolytically processed in the kidney. This fatty acid-binding protein could not be immunologically detected in female rat kidney.Keywords
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