The Hamman-Rich Syndrome

Abstract
SINCE the report of Hamman and Rich1 , 2 of a disease characterized by diffuse interstitial fibrosis of the lungs, the clinical syndrome and the characteristic pathology have been well defined. This condition, now popularly known as the Hamman-Rich syndrome, is generally considered to be of unknown etiology, although various theories have been propounded. Originally, it was thought to be related to a viral infection or a hypersensitivity reactions.1 , 2 Interstitial fibrosis of the lungs also occurs after attacks of influenzal pneumonia, scrub typhus or exposure to various chemical irritants. Recently, a similar clinicopathological condition was observed after therapy for hypertension with hydralazine. . . .