Two- and Three-dimensional MR Coronary Angiography with Intraarterial Injections of Contrast Agent in Dogs: A Feasibility Study

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Abstract
Magnetic resonance (MR) images of coronary arteries were acquired with an inversion recovery-prepared technique after intraarterial injection of contrast material in five dogs. Real-time two-dimensional projection images were obtained with a temporal resolution of 3 frames per second. Three-dimensional electrocardiographically triggered high-spatial-resolution images were obtained with a fraction of the contrast agent required for intravenous injections. Background tissues were adequately suppressed in all images. On the basis of this experimental data, the optimal contrast agent concentration for two-dimensional real-time projection imaging was 6%. This preliminary work shows that contrast material-enhanced MR angiography with intraarterial injections is feasible with the proposed techniques.