Molecular and Physiological Bases of the K+ Circulation in the Mammalian Inner Ear
- 1 October 2006
- journal article
- review article
- Published by American Physiological Society in Physiology
- Vol. 21 (5) , 336-345
- https://doi.org/10.1152/physiol.00023.2006
Abstract
Endolymph, the extracellular solution in cochlea, contains 150 mM K+ and exhibits a potential of approximately +80 mV relative to neighboring extracellular spaces. This unique situation, essential for hearing, is maintained by K+ circulation from perilymph to endolymph through the cochlear lateral wall. Recent studies have identified ion-transport molecules involved in the K+ circulation and their pathophysiological relevance.Keywords
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