Purine- and Pyrimidine-Specific Antibodies: Effect on the Fertilized Sea Urchin Egg
- 17 July 1964
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 145 (3629) , 282-283
- https://doi.org/10.1126/science.145.3629.282
Abstract
Antiserums from rabbits immunized with several purine- and pyrimidine-containing albumin conjugates can penetrate and become fixed within cells of Arbacia punctulata. All of these specific antiserums were found to inhibit embryonic development of the fertilized sea urchin egg. The stage of arrestment of development was dependent in part upon the dilution of antiserum, and also upon the nature of its specificity. It is suggested that the observed results reflect the interaction of these antiserums with singlestranded DNA within the cell.Keywords
This publication has 7 references indexed in Scilit:
- THE MANIPULATIONS OF MACROMOLECULAR SUBSTANCES DURING FERTILIZATION AND EARLY DEVELOPMENT OF ANIMAL EGGSAmerican Zoologist, 1963
- Messenger Ribonucleic AcidProgress in Nucleic Acid Research and Molecular Biology, 1963
- Biologic Synthesis of Deoxyribonucleic AcidScience, 1960
- The American Arbacia and other sea urchinsPublished by Biodiversity Heritage Library ,1956
- LOCALIZATION OF ANTIGEN IN TISSUE CELLSThe Journal of Experimental Medicine, 1950
- The coalescence of living cells with oil drops. II. Arbacia eggs immersed in acid or alkaline calcium solutionsJournal of Cellular and Comparative Physiology, 1937
- The coalescence of living cells with oil drops. I. Arbacia eggs immerised in sea waterJournal of Cellular and Comparative Physiology, 1937