DNA cleavage by a ‘metalloporphyrin-spermine-oligonucleotide’ molecule
- 1 January 1995
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 2,p. 181-182
- https://doi.org/10.1039/c39950000181
Abstract
A ‘manganese porphyrin-spermine-oligonucleotide’ molecule, forms a stable triple helix structure (Tm= 42 °C), and cleaves a double-stranded DNA sequence of HIV-1.Keywords
This publication has 23 references indexed in Scilit:
- "Redox Tautomerism" in High-Valent Metal-oxo-aquo Complexes. Origin of the Oxygen Atom in Epoxidation Reactions Catalyzed by Water-Soluble MetalloporphyrinsJournal of the American Chemical Society, 1994
- G-Wires: Self-Assembly of a Telomeric Oligonucleotide, d(GGGGTTGGGG), into Large SuperstructuresBiochemistry, 1994
- Selectivity of polyamines in triplex DNA stabilizationBiochemistry, 1993
- Nonenzymic cleavage and ligation of DNA at a three A.cntdot.T base pair site. A two-step pseudohydrolysis of DNAJournal of the American Chemical Society, 1993
- Targeted chemical nucleasesAccounts of Chemical Research, 1993
- Chemically Modified Oligonucleotides as Probes and InhibitorsAngewandte Chemie International Edition in English, 1991
- A sodium-potassium switch in the formation of four-stranded G4-DNANature, 1990
- Sequence-targeted photochemical modifications of nucleic acids by complementary oligonucleotides covalently linked to porphyrinsBioconjugate Chemistry, 1990
- Sequence-Specific Cleavage of Double Helical DNA by Triple Helix FormationScience, 1987
- Nucleotide sequence of the AIDS virus, LAVCell, 1985