HERPETIC ENDOTHELIAL KERATITIS

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Abstract
The corneal endothelium of a 60 yr old male with acute anterior uveitis following typical dendritic keratitis was studied by specular microscopy. The epithelial dendritic ulcer of the left cornea healed within 10 days with topical trifluorothymidine treatment. At 6 wk later the same eye became red and painful and anterior uveitis was diagnosed. Changes in the endothelium suggested that endothelitis was also present. The nonreflecting black endothelial areas were documented as a new sign by specular microscopy. The black areas disappeared in 3 days with topical trifluorothymidine and corticosteroid treatment. The pathomechanism of these transient black areas is discussed. [Herpes simplex virus was the cause of these manifestations.].

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