Macrocyclic enzyme model system: catalysis of ester degradation by a [20]paracyclophane bearing nucleophilic and metal-binding sites
- 1 January 1978
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 12,p. 494-496
- https://doi.org/10.1039/c39780000494
Abstract
When the [20]paracyclophane (1) bearing oxime and imidazole groups is bound to Cu2+ ion with the latter species in a moderate pH region, the resulting CuII complex shows esterase-like activity; the un-ionized oxime group is acylated with the assistance of the co-ordinated Cu2+ ion.Keywords
This publication has 1 reference indexed in Scilit:
- Mechanism of action of carboxypeptidase A in ester hydrolysis.Proceedings of the National Academy of Sciences, 1976