Abstract
It appears that the so-called mesothelium lining the serous cavities [in humans] is in fact mesoderm, with an epithelial-like arrangement which persists in the post-embryological stage. Cellular variability of primary tumors of serous surfaces can be explained on this developmental evidence. The term mesodermoma seems to be justified to define neoplasms arising from undifferentiated and multipotential mesoderm which, in neoplastic disease, exhibits a wide range of differential activity and gives rise to tumors with prevailing myoblastic, angioblastic, lymphoblastic, chondroblastic, osteoblastic, fibroblastic or epithelial-like features.

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