Nosocomial Transmissibility of Nipah Virus

Abstract
To the Editor—A severe outbreak of fatal viral encephalitis mainly affecting pig farmers occurred in Malaysia in 1999. The outbreak was due to Nipah virus, a novel paramyxovirus [1]. Nipah virus was isolated from the upper respiratory tract secretions and urine of 8 of 20 patients with acute encephalitis [2]. Mounts et al. [3] found that 3 of 338 health care workers who were exposed to patients during the outbreak were positive for IgG antibodies, as determined by EIA. The 3 positive serum samples did not have an IgM response and were negative for anti–Nipah virus neutralizing antibodies; thus, the authors inferred that the results were likely to be false positives and commented that the lack of nosocomial transmission to the health care workers was somewhat unexpected