SAFETY ASPECTS OF HANDLING THE POTENT ALLERGEN FDNB

Abstract
The potent allergen, 1-fluoro-2,4-dinitrobenzene is widely used in biochemical research and teaching for characterization of amines, especially amino acids, and for experimental immunization. Experimental observations and clinical reports are reviewed and factors influencing [human] sensitization are discussed. Taking these into account, recommendations are given for the proper use of protective gloves and avoidance of spray inhalation when using the reagent.

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