The Study of Aqueous Extract of Puerariae Radix. IV. The Isolation of Daidzin from the Active Extract (MTF-101) and Its Antifebrile and Spasmolytic Effect
Open Access
- 1 January 1977
- journal article
- research article
- Published by Pharmaceutical Society of Japan in YAKUGAKU ZASSHI
- Vol. 97 (1) , 103-105
- https://doi.org/10.1248/yakushi1947.97.1_103
Abstract
From the aqueous extract (MTF-101) of Pueraria radix, daidzin (daidzein-7-glucoside) was isolated in 0.14% yield. The hypothermic effect of daidzin on rats and its spasmolytic effect on mice were examined in comparison with those of daidzein. Neither daidzin nor daidzein showed a hypothermic effect in a dose of 30 mg/kg s.c. on rats. Daidzein showed about 1/3 spasmolytic effect of papaverine on the small intestine of mice but daidzin showed no spasmolytic effect.Keywords
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