Steady-state pharmacokinetics and tolerability of orally administered fampridine sustained-Release 10-mg tablets in patients with multiple sclerosis: A 2-week, open-label, follow-up study
- 31 October 2009
- journal article
- Published by Elsevier in Clinical Therapeutics
- Vol. 31 (10) , 2215-2223
- https://doi.org/10.1016/j.clinthera.2009.10.007
Abstract
No abstract availableKeywords
This publication has 28 references indexed in Scilit:
- Potassium channel blockers in multiple sclerosis: Neuronal Kv channels and effects of symptomatic treatmentPharmacology & Therapeutics, 2006
- Phase 2 trial of sustained-release fampridine in chronic spinal cord injurySpinal Cord, 2006
- Randomized trial of 4-aminopyridine in patients with chronic incomplete spinal cord injuryZeitschrift für Neurologie, 2001
- Absorption Characteristics of Sustained‐Release 4‐Aminopyridine (Fampridine SR) in Patients with Chronic Spinal Cord InjuryThe Journal of Clinical Pharmacology, 2000
- Safety and Efficacy of 4‐Aminopyridine in Humans with Spinal Cord Injury: A Long‐Term, Controlled TrialPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1999
- Sustained improvements in neurological function in spinal cord injured patients treated with oral 4-aminopyridine: three cases.Spinal Cord, 1998
- Differential effects of low and high concentrations of 4-aminopyridine on axonal conduction in normal and injured spinal cordNeuroscience, 1997
- 4-Aminopyridine in Chronic Spinal Cord Injury: A Controlled, Double-Blind, Crossover Study in Eight PatientsJournal of Neurotrauma, 1993
- 4-aminopyridine leads to restoration of conduction in demyelinated rat sciatic nerveBrain Research, 1985
- The mode of action of 4-aminopyridine and guanidine on transmitter release from motor nerve terminalsEuropean Journal of Pharmacology, 1977