Variant Translocations of Chromosome 13 in Alveolar Rhabdomyosarcoma
- 1 November 1991
- journal article
- research article
- Published by Wiley in Genes, Chromosomes and Cancer
- Vol. 3 (6) , 480-482
- https://doi.org/10.1002/gcc.2870030611
Abstract
In three cases of alveolar rhabdomyosarcoma with variant translocations, two tumors contained an identical translocation, t(1;13)(p36.1;q14); the third tumor contained a t(8;13)(p21;q14). All three patients were 2 years old, markedly younger than the median age for patients with t(2; 13)-positive alveolar rhabdomyosarcoma. The alteration of genetic material on chromosome 13 may be of primary importance in the development of alveolar rhabdomyosarcoma.Keywords
This publication has 3 references indexed in Scilit:
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