β-Lactamase Gene Expression in a Penicillin-Resistant Bacillus anthracis Strain
Open Access
- 1 December 2004
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 48 (12) , 4873-4877
- https://doi.org/10.1128/aac.48.12.4873-4877.2004
Abstract
Expression of the bla1 and bla2 genes in an archetypal Bacillus anthracis strain is insufficient for penicillin resistance. In a penicillin-resistant clinical isolate, both genes are highly transcribed, but bla1 is the major contributor to high-level resistance to ampicillin. Differential expression of the bla genes is dependent upon strain background.Keywords
This publication has 34 references indexed in Scilit:
- Biochemical Characterization of β-Lactamases Bla1 and Bla2 from Bacillus anthracisAntimicrobial Agents and Chemotherapy, 2003
- β-Lactamase Genes of the Penicillin-SusceptibleBacillus anthracisSterne StrainJournal of Bacteriology, 2003
- Antibiotic Susceptibilities of 96 Isolates of Bacillus anthracis Isolated in France between 1994 and 2000Antimicrobial Agents and Chemotherapy, 2002
- The fate of the BlaI repressor during the induction of the Bacillus licheniformis BlaP β‐lactamaseMolecular Microbiology, 2002
- Antimicrobial Susceptibility of Bacillus anthracis in an Endemic AreaScandinavian Journal of Infectious Diseases, 2002
- The atxA gene product activates transcription of the anthrax toxin genes and is essential for virulenceMolecular Microbiology, 1995
- The dam and dcm strains of Escherichia coli — a reviewGene, 1994
- Cutaneous anthrax due to penicillin-resistant Bacillus anthracis transmitted by an insect biteThe Lancet, 1992
- A fatal case of pulmonary anthrax.BMJ, 1976
- A fatal case of cutaneous anthraxEpidemiology and Infection, 1974