Tissue-specific expression of the rat alpha 2u globulin gene family.

1 October 1986

journal article
research article
Published by Taylor & Francis in Molecular and Cellular Biology

Vol. 6 (10) , 3563-3567
https://doi.org/10.1128/mcb.6.10.3563

Abstract

The rat .alpha.2u globulin gene family encodes approximately 20 low-molecular-weight (20,000) proteins with pIs ranging from 4.5 to 7.9. .alpha.2u globulin protein isoforms were detected in the liver and in the submaxillary, lachrymal, preputial, and mammary glands of Sprague-Dawley rats. The hormonal and developmental regulation of .alpha.2u globulin synthesis in each of these tissues was unique, and it appears that different .alpha.2u gene sets were transcribed in the various tissues.

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