Radioactive oxygen 15 in study of kinetics of oxygen of respiration
- 1 September 1961
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 201 (3) , 582-586
- https://doi.org/10.1152/ajplegacy.1961.201.3.582
Abstract
Among the major components of living matter, oxygen is the only one which has not, heretofore, been extensively traced by means of radioactive techniques. A system for the production and purification of radioactive oxygen 15 has been developed. Oxygen 15 decays with a half-life of 2.25 min by the emission of positrons. The isotope is prepared by irradiation of nitrogen by means of cyclotron-accelerated deuterons. Air tagged with O15 has been applied to the study in dogs of a) the kinetics of the transfer of oxygen from pulmonary gases to blood, b) the rate of incorporation of oxygen into water during metabolism, c) the rate of exchange of plasma water with tissue water.Keywords
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