Gonadotrophin Levels in Male Rats Following Impairment of Leydig Cell Function by Ethylene Dimethanesulphonate
- 24 April 2009
- journal article
- Published by Hindawi Limited in Andrologia
- Vol. 9 (1) , 29-35
- https://doi.org/10.1111/j.1439-0272.1977.tb01255.x
Abstract
The effects of the antispermatogenic compound, ethylene dimethanesulphonate on anterior pituitary and serum FSH, LH and prolactin levels in male rats were investigated. A rapid and sustained rise in serum LH, reaching castrate levels, indictated a normal pituitary response to androgen deprivation. Whilst no change in prolactin was observed, serum FSH showed a biphasic increase which is discussed in relation to the spermatogenic process.Keywords
This publication has 7 references indexed in Scilit:
- InhibinPublished by Elsevier ,1977
- Suppression of testicular androgen synthesis in the rat by ethane 1,2, dimethanesulphonateJournal of Steroid Biochemistry, 1975
- Serum Gonadotropin and Testosterone Levels During Loss and Recovery of Spermatogenesis in Rats1Endocrinology, 1973
- HORMONAL ANTAGONISM TO THE ANTISPERMATOGENIC EFFECT OF ETHYLENEDIMETHANESULPHONATE IN RATSReproduction, 1973
- Pituitary and Serum FSH and LH Levels after Massive and Selective Depletion of the Germinal Epithelium in the Rat Testis*Endocrinology, 1973
- COMPARATIVE EFFECTS OF METHYLENE, ETHYLENE AND PROPYLENE DIMETHANESULPHONATES ON THE MALE RAT REPRODUCTIVE SYSTEMReproduction, 1970
- THE PREPARATION OF 131I-LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC RADIOACTIVITYBiochemical Journal, 1963