Meiotic chromosome condensation and pairing in Saccharomyces cerevisiae studied by chromosome painting
- 1 October 1992
- journal article
- Published by Springer Nature in Chromosoma
- Vol. 101 (10) , 590-595
- https://doi.org/10.1007/bf00360535
Abstract
Non-isotopic high resolution in sity hybridization was applied to cytological preparations of sporulating yeast cells. Ribosomal DNA (rDNA) and chromosome V-specific recombinant lambda clones were used to tag individual chromosomes and chromosome subregions. This allowed the study of chromosome behaviour during early meiotic prophase. It was found that chromatin becomes condensed and homologous DNA sequences then appear to become aligned prior to synaptonemal complex formation.Keywords
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