Medical Therapy of True Precocious Puberty due to Hamartoma of the Tuber cinereum

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Abstract
2 patients with true precocious puberty and hamartoma of the tuber cinereum are described. Diagnosis was established by the presence of accelerated puberty, elevated blood gonadotropins, without other evidence of central nervous system dysfunction and positive computed tomography scans. 2 patients were treated with cyproterone acetate and abstention from surgery was achieved with close observation of the tumor’s size by computed tomography.

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