Determining the structure and mechanism of the human multidrug resistance P-glycoprotein using cysteine-scanning mutagenesis and thiol-modification techniques
- 29 November 1999
- journal article
- review article
- Published by Elsevier in Biochimica et Biophysica Acta (BBA) - Biomembranes
- Vol. 1461 (2) , 315-325
- https://doi.org/10.1016/s0005-2736(99)00165-0
Abstract
No abstract availableKeywords
This publication has 76 references indexed in Scilit:
- A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutantsPublished by Elsevier ,2003
- The P-Glycoprotein Efflux Pump: How Does it Transport Drugs?The Journal of Membrane Biology, 1997
- The physiological function of drug-transporting P-glycoproteinsSeminars in Cancer Biology, 1997
- P-glycoprotein and multidrug resistanceCurrent Opinion in Genetics & Development, 1996
- Diagnosis and reversal of multidrug resistance in paediatric cancersEuropean Journal Of Cancer, 1996
- Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugsPublished by Elsevier ,1994
- The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues.Molecular and Cellular Biology, 1989
- Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites.Proceedings of the National Academy of Sciences, 1989
- The tissue dependent expression of hamster P‐glycoprotein genesFEBS Letters, 1988
- Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues.Proceedings of the National Academy of Sciences, 1987