A PROGNOSTIC INDEX BASED ON THE MEAN NUCLEAR-AREA OF BREAST-CANCER CELLS AND EFFERENT VASCULAR INVASION IN THE AXILLARY NODES

  • 1 January 1983
    • journal article
    • research article
    • Vol. 6  (3-4) , 221-228
Abstract
Statistical evaluation of the prognostic impact of different variants of the mean nuclear area (MNA) of tumor cells in [human] breast carcinoma was used to find an optimal combination for use in conjunction with the absence/presence of tumor cells in the efferent vessels of the axillary nodes (EVI). This model gives an estimate of the relative prognostic impact of the different variables and their reliability. Combination of EVI with MNA of the primary tumor gave the optimal prediction of disease outcome; 81% correct prediction before 60 mo., falling to 73% by 98 mo. after the operation.